Journal of Oral Cancer and Research

Prospective Pilot Clinical Trial Pages 72-76

Does Clinical or Radiologic Exam Better Predict Carcinomatous Invasion of the Jaw?

Authors: Elliot Cherkas, BA, Rapheal Banoub, MD, Madalina Tuluc, MD, Neeta Rao, MD, Majid Khan, MD, Allen Champion, DDS and James C Gates DMD MD

Abstract: Clinical and radiologic exam are critical to determine the extent of invasion from oral squamous cell carcinoma. In this study, we examine their accuracy in the prediction of invasion of the maxilla or mandible, as judged using histopathologic correlation. We enrolled patients into a prospective, phase one, clinical trial. The predictor variables were clinical and radiologic examination. The experimental variable was the use of cone beam CT to predict invasion of the jaw. Each variable was assessed for sensitivity, specificity, as well as diagnostic accuracy.

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